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Units > Medical Immunology > Course Materials


​Lecture 1: Introduction to Immunity (Click to view)
  • Self and non-self recognition
  • Immune specificity & diversity
  • Innate & adaptive immune response
  • Cells of the immune system


Lecture 2: Innate Immunity (Click to view)
  • Receptor ligand interaction
  • Different types of antigens
  • Different types of receptors
  • The natural barriers to infections
  • The normal flora


Lecture 3: Innate Immune Function (Click to view)
  • Recognition
  • Soluble defence mechanisms
  • Cellular defence mechanism


Lecture 4: Adaptive Immunity (Click to view)
  • Immunoglobulins
  • Complement system
  • Major Histocompatibility Complex (MHC)
  • T-Cell Receptors (TCR)
  • Molecules of cellular interactions


Lecture 5: Cellular Development of the Immune System (Click to view)
  • Lymphocyte development
  • Bone marrow & spleen
  • Primary lymphoid tissues
  • Secondary lymphoid organs
  • Immunological diversity


Lecture 6: Activation of Immune Response (Click to view)
  • Antigen presentation and processing
  • MHC Complex types I & II
  • T cell activation
  • B cell activation
​

Lecture 7: Effector Function of the Immune System (Click to view)
  • Types of protective Immunity
  • Humoral Immunity
  • Cell-Mediated Immunity
  • Immunological Memory


Lecture 8: Regulation of the Immune Response (Click to view)
  • Immune tolerance
  • Central & peripheral tolerance
  • T & B Cell tolerance
  • Regulatory cells of the immune system
  • The action of regulatory cytokine


Lecture 9: Immunity & Health (Click to view)
  • Cellular and molecular recirculation
  • Responses to infectious agents
  • Case study: Rhinovirus infection
  • Inflammation
  • Mucosal Immunity​


Lecture 10: Hypersensitivity (Click to view)
  • What is Hypersensitivity
  • Classification of Hypersensitivity
  • Pathophysiology of each type
  • Assessment of hypersensitivity
​
​
Lecture 11: Transplantation (Click to view)
  • Transplantation immunity
  • MHC complex involvement
  • Immune response after transplantation
  • Graft vs. Host Disease (GVHD)


Lecture 12: Autoimmune Diseases (Click to view)
  • Causes & Pathogenesis
  • Pathogenic effects of B & T cells
  • HLA association in autoimmune diseases
  • Case study: Rheumatoid arthritis & SLE


Lecture 13: Immunodeficiency (Click to view)
  • What is Immunodeficiency
  • Congenital Immunodeficiency
  • Acquired Immunodeficiency
  • Case study: Acquired Immunodeficiency Syndrome (AIDS)

Lecture 14: Cancer Immunity (Click to view)



► Animation by Wiley-Blackwell (click to follow the link)
Copyright ©2011. John Wiley & Sons Ltd


► Additional Resources:

  • The process by which some WBCs exit the blood stream to enter the tissue.

  • The process by which Antigen Presenting Cells (APCs) present pathogenic antigens to other WBCs.

  • The process by which Antigen Presenting Cells (APCs) present pathogenic antigens to other WBCs.

  • The activation of immature T cells.

  • The activation of immature B cells.

  • The activation of immature B cells.
Animations by © Murphy et al. Janeway's immunobiology. Garland Science, 2012.
Videos by Doan et al. Lippincott’s Illustrated Reviews: Immunology. Wolters Kluwer, 2013.

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