Units > Molecular & Medical Genetics > Course Materials

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Lecture 1 (Introduction to Genetics): (Click to view)

• Gregor Mendel
• What is Genetics
• Natural Selection
• Why is Genetics important

Lecture 2 (Genes & Chromosomes): (Click to view)

• Cell Division: Meiosis & Mitosis
• Autosomes & Sex Chromosomes
• Karyotyping and FISH
• Genes: Introns & Exons
• Gene Structure

Lecture 3 (DNA & RNA): (Click to view)

• Structure & Function of DNA
• Structure & Function of RNA
• The Central Dogma
• DNA Replication 

Lecture 4 (The Genetic Code): (Click to view)

• The Flow of Information (Genetic Code)
• Promoter Regions and Regulatory Elements
• Transcription and RNA Processing
• Translation & Post-Transnational Modifications

Lecture 5 (Modes of Inheritance): (Click to view)

• Mendel's Genetics
• The Law of Segregation
• The Law of Independent Assortment
• The law of Dominance
• Non Mendelian Inheritance

Lecture 6 (Chromosomal Abnormalities): (Click to view)

• Normal Karyotype
• Numerical Abnormalities
• Structural Abnormalities
• Genetic Disease

Lecture 7 (Chromosomal Abnormalities: Case Study): (Click to view)

• Down Syndrome: Trisomy 21
• Pathology of Down Syndrome
• Diagnosis of Genetic Disease
• Prenatal Testing

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Lecture 8 (Mutations): (Click to view)

• Types of DNA Mutations
• DNA Polymorphism
• Difference between Genetic & Epigenetic Chanages Effects
• Phenotypic & Genotypic Effects

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Lecture 9 (Sickle Cell Anemia: case study): (Click to view)

Lecture 10 (Cancer Genetics): (Click to view)

Lecture 11 (Diagnostic Techniques: Pedigree): (Click to view)

Lecture 12 (Diagnostic Techniques: Prenatal Testing): (Click to view)

Lecture 13 (Diagnostic Techniques: Cytogenetics & FISH): (Click to view)

Lecture 14 (Diagnostic Techniques: Sequencing): (Click to view)

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► Additional Resources:

• Click here for a step-by-step demonstration on how to IF-AT (Scratch cards) works

• DNA replication, transcription and RNA translation: 3D Animation (by CSHL)

• Difference between Meiosis & Mitosis:

 

• DNA & Chromatin Formation (© WEHI) :

• DNA Replication:

• Gregor Mendel and the Principles of Inheritance
  

• Genetic Diagnosis: DNA Microarrays and Cancer

• Egton Medical Information Systems UK: Prenatal Screening for Down's Syndrome

• Standardized Human Pedigree Nomenclature

• Nature Education: Translation: DNA to mRNA to Protein

• Nature Education: Cytogeneticists can now go "FISH-ing" for chromosomal abnormalities

• DNA Transcription (© CSHL)

 

• mRNA Translation (© CSHL)

 

• Transcription & Translation Animation (© UIC.edu)